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Managing Perimenopause With Asthma

Asthma symptoms can change significantly during perimenopause. Learn how hormonal shifts affect your airways and how to manage both conditions.

5 min readFebruary 28, 2026

A Hormonal Influence on the Airways

Asthma is more common in women than men after puberty, and its severity tends to fluctuate with the menstrual cycle, pregnancy, and menopause, all of which point to a strong hormonal influence on airway behaviour. Oestrogen and progesterone both affect the airways: oestrogen generally has anti-inflammatory effects and may reduce airway reactivity, while progesterone influences breathing drive and has bronchodilatory properties. During perimenopause, unpredictable shifts in both hormones can make asthma control less predictable, even in women who have managed the condition well and consistently for many years. For some, perimenopause is the first time their asthma becomes a significant problem.

How Perimenopause Changes Asthma Control

Many women with asthma notice meaningful changes in their symptom patterns during perimenopause. Some experience worsening control, with more frequent wheezing, chest tightness, shortness of breath, or night-time coughing. Others find that asthma becomes more reactive to triggers that previously caused little trouble. Hormonal fluctuations appear to increase airway inflammation and sensitivity in some women, particularly around the perimenstrual phase of an increasingly irregular cycle. A subset of women develop asthma for the first time in their late 40s, a presentation sometimes referred to as late-onset asthma, which in certain cases appears linked to the hormonal changes associated with perimenopause. Any new respiratory symptoms should be assessed rather than attributed to hormones alone.

Night-Time Symptoms and Sleep Disruption

Asthma already has a recognised nocturnal component, with symptoms tending to worsen in the early hours of the morning due to natural dips in cortisol and physiological changes in airway calibre that occur during sleep. Perimenopause compounds this pattern through night sweats that disturb sleep repeatedly, raise stress hormones, and cause breathing pattern changes as the body attempts to thermoregulate after a hot flash. Women managing both conditions often find that improving sleep quality, through whatever combination of strategies addresses their night sweats most effectively, also produces an improvement in nocturnal asthma symptoms. Tracking nights where breathlessness or coughing wakes you can help clarify whether the trigger is primarily hormonal, asthma-related, or both together.

Staying Physically Active With Asthma

Regular exercise benefits both asthma and perimenopausal wellbeing, and the evidence for exercise as a positive influence on asthma control is well established. Exercise-induced bronchoconstriction can be a real barrier for some women, but it is generally manageable rather than a reason to avoid activity. Using a short-acting bronchodilator inhaler fifteen to twenty minutes before planned exercise, as agreed with your doctor or asthma nurse, allows most women to stay physically active without triggering significant symptoms. Swimming in an indoor pool is often recommended for people with asthma because the warm, humid air around the pool is less provocative for airways than cold, dry outdoor air. Building fitness gradually and warming up properly before more intense sessions reduces exercise-induced symptoms.

Reviewing Your Asthma Action Plan

If your asthma control has changed during perimenopause, this is a practical and important time to review your asthma management plan with your GP or respiratory nurse. Your preventer inhaler dose may need adjusting, or additional controller medications may be appropriate given your changed symptom pattern. Peak flow monitoring at home provides objective data on airway function day to day and can reveal drifting control before it becomes a full exacerbation. Bringing peak flow records and a symptom log to your review appointment makes the consultation considerably more productive than describing symptoms from memory and helps your clinician understand how your asthma is behaving across different weeks and phases of your cycle.

HRT and Asthma: What the Evidence Shows

The relationship between HRT and asthma is not yet fully settled in the research literature, and available studies show mixed results depending on the type of HRT, the dose, the route of administration, and the individual. Some studies have suggested that oestrogen-only HRT may worsen asthma in a subset of women, while other research indicates no significant effect on airway function. Combined HRT results also vary. This uncertainty means that for women with asthma, the decision about HRT should weigh overall symptom burden and quality of life against the possibility of any change in asthma control, which can be monitored closely if HRT is started. Discussing this with both your menopause specialist and your GP or respiratory clinician before starting is a sensible step.

Managing Both Conditions Long Term

Managing asthma and perimenopause simultaneously requires ongoing flexibility and good communication with your healthcare team across both conditions. Both benefit from consistent daily routines, adequate sleep, stress reduction, and avoiding known triggers. If your asthma symptoms are changing during perimenopause, act on that observation promptly rather than attributing everything to hormones and waiting it out. Keeping a record of your symptoms, peak flow readings, and activity over time gives you the kind of detailed data that supports better clinical decisions and makes your own self-management more informed. Perimenopause is a transitional phase, and the habits built for managing both conditions through it will serve you well on the other side.

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Medical disclaimerThis content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. PeriPlan is not a substitute for professional medical advice. If you are experiencing severe or concerning symptoms, please contact your doctor or emergency services immediately.

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