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HRT Implants vs. Patches: Which Delivery Method Is Right for You?

Comparing HRT implants and patches for perimenopause? Learn how each works, the key differences in dosing and convenience, and how to talk to your doctor.

7 min readFebruary 27, 2026

So Many Options, So Little Clear Guidance

You have decided to explore hormone replacement therapy. Your doctor has mentioned patches, or perhaps implants, and now you are trying to figure out what each actually means in practice. What goes into your body, how often, and at what cost, both financially and in terms of effort?

HRT comes in more delivery forms than most people realize: pills, patches, gels, sprays, and implants, each with a different mechanism for getting hormones into your system. Patches and implants are both non-oral options that bypass the liver, but they work quite differently. Understanding those differences helps you have a more informed conversation with your prescribing clinician.

What HRT Patches and Implants Have in Common

Both patches and implants are transdermal or subcutaneous methods, meaning they bypass the digestive system and deliver hormones directly into your bloodstream. This is considered an advantage over oral HRT because it avoids the first-pass liver metabolism that pills require. Research has examined non-oral routes and their potentially lower association with blood clot risk compared to oral tablets, though individual risk profiles always matter.

Both options can deliver estrogen alone or in combination with progestogen, depending on whether you have a uterus. Both aim to smooth out hormonal fluctuations rather than adding sharp peaks and troughs. And both require a prescription and monitoring by a qualified healthcare provider.

How Patches Work

Estrogen patches are adhesive squares or circles, similar to a large plaster, applied to a low-abdomen or buttock area of skin. They come in different strengths and are typically changed every one to three days for daily patches, or every three to four days for twice-weekly patches, depending on the formulation. The hormone absorbs steadily through the skin throughout the wear period.

Patches are widely available, well-studied, and reversible: if you experience side effects or change your mind, you simply remove the patch and hormone levels start to drop within days. They can be purchased through standard pharmacy systems in most countries with a prescription. The main practical challenges are skin reactions at the adhesion site and remembering to change them on schedule.

How Implants Work

Implants are small pellets, roughly the size of a grain of rice, inserted under the skin, usually in the lower abdomen or buttock, by a clinician using a minor outpatient procedure with local anesthetic. They release hormones steadily over several months, typically three to six months, before needing replacement. Both estrogen-only and testosterone implants are available, though testosterone implants in particular are more of a specialist area.

The main advantage is convenience: once the implant is in, you do not think about it. There is no daily or twice-weekly routine. Hormone levels from implants tend to be consistent, though they can be higher than patch dosing in some cases. The significant caveat is that implants are not easily reversible. If you experience unwanted side effects, you cannot simply remove the implant in the way you can take off a patch. You need to wait for it to run down, or in rare cases have it physically removed.

Key Practical Differences

Reversibility is the most clinically important difference. Patches offer flexibility that implants do not. If a particular dose does not suit you, dose adjustment is straightforward with patches. With implants, adjusting is more complicated.

Implants are less widely available than patches. They are typically offered through specialist menopause clinics or private providers rather than standard GP prescribing in many healthcare systems. Cost and access vary significantly depending on where you live and whether you are using a private clinic or a public health service. Patches, by contrast, are typically available through a standard GP or OB/GYN prescription.

Hormone level monitoring matters more with implants. Because implant dosing can result in higher and less predictable hormone levels in some women, blood level testing before each re-implantation is important. Some women find their hormone levels remain elevated for longer than expected, which can complicate the timing of replacements.

Can You Switch Between Methods?

Yes, and many women do. You might start with patches to find a dose that suits you, then explore other options later. Switching from patches to implants is possible, though your clinician will want to confirm your previous dosing before selecting an implant strength. Switching in the other direction, from implants to patches, requires waiting for implant levels to decline first.

Some women use implants for estrogen and add a topical or oral progestogen separately if they have a uterus. This kind of combination approach is something to discuss with a menopause specialist who can tailor a regimen to your specific situation.

Track Your Symptoms Across Treatment Changes

When you change HRT methods or doses, tracking your symptoms carefully helps you assess whether the new approach is working. Some symptoms improve quickly; others may take weeks or months. Knowing what changed and when gives you and your doctor useful information.

PeriPlan lets you log symptoms and track patterns over time. Logging daily how you feel, alongside any changes to your HRT regimen, creates a clear record of what is helping, what is not, and how quickly changes take effect.

When to See Your Doctor

Seek review from your prescribing clinician if you are experiencing breakthrough symptoms between patch changes, as this may suggest the dose needs adjusting or the patch type switching. If you have an implant and experience unwanted side effects, contact your provider rather than waiting for the implant to run down on its own.

Anyone considering implants should ensure they are under the care of a clinician experienced with this delivery route and who will arrange hormone level monitoring. Implants are not suitable as an unsupervised or self-managed treatment.

The Right Option Is the One That Works for Your Life

There is no universally better choice between patches and implants. The right option depends on your lifestyle, your preferences, your access to specialist care, and your response to different hormone levels. What matters most is that you find a form of HRT that keeps your symptoms manageable and fits into your daily life without being a source of stress.

A menopause-informed clinician can help you weigh these options for your specific situation. You are entitled to a conversation that covers the evidence, the practicalities, and your own priorities.

This content is for informational purposes only and does not replace medical advice. Always consult your healthcare provider about your specific situation.

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Medical disclaimerThis content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. PeriPlan is not a substitute for professional medical advice. If you are experiencing severe or concerning symptoms, please contact your doctor or emergency services immediately.

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