Articles

Best Sleep Supplements for Perimenopause in the UK

A practical guide to the best sleep supplements for perimenopause available in the UK, covering magnesium, ashwagandha, valerian, and more.

5 min readFebruary 28, 2026

Why Sleep Becomes So Difficult During Perimenopause

Sleep disruption is one of the most commonly reported symptoms of perimenopause, affecting the majority of women at some point during the transition. Fluctuating oestrogen and progesterone levels interfere with the brain's sleep architecture, making it harder to fall asleep, stay asleep, or achieve the deep restorative stages of sleep. Night sweats compound the problem by waking women from sleep at irregular intervals. Anxiety, which also rises during perimenopause, adds another layer of difficulty by keeping the mind alert when the body is trying to wind down. While no supplement replaces good sleep hygiene or, where appropriate, medical treatment, several have good evidence for modest, meaningful benefit in this context. UK availability is noted throughout, as product ranges differ from those in North America.

Valerian Root: A Traditional Herbal Option

Valerian root has been used as a sleep aid in European herbal medicine for centuries and is widely available in UK pharmacies and health shops. The evidence is mixed, with some studies showing benefit for sleep onset and quality and others showing no significant effect compared to placebo. It appears to work best for women whose sleep difficulty is primarily driven by anxiety or restlessness rather than night sweats. Valerian is generally considered safe for short-term use and can be taken as a capsule, tablet, or tea. Dosages in clinical studies range from 300 to 600mg taken 30 minutes to two hours before bed. It is one of the more affordable herbal sleep options available over the counter in the UK.

L-Theanine: Calm Without Sedation

L-theanine is an amino acid found naturally in green tea and available as a standalone supplement. It promotes a state of relaxed alertness by increasing alpha brain wave activity, which is the pattern associated with a calm, focused mind rather than drowsiness. For women whose sleep problem is primarily driven by a racing mind or anxious thinking at bedtime, L-theanine can help quiet mental activity without causing morning grogginess. It is often combined with magnesium in sleep-specific formulations. A typical dose is 100 to 200mg taken in the evening. L-theanine has a very good safety profile and is well-tolerated even at higher doses. It is available from most UK supplement retailers and does not interact with common medications.

Melatonin: What UK Women Need to Know

Melatonin is available over the counter at low doses in many countries, but in the UK it is a prescription-only medicine, which means you cannot buy standard melatonin supplements legally from a high street shop or online UK retailer. A GP can prescribe it for short-term use in specific circumstances, including jet lag and some sleep disorders. For perimenopause-related sleep disruption, a conversation with your GP about whether melatonin is appropriate for your situation is worthwhile. Some women find it useful for resetting a disrupted sleep cycle or managing night sweats that wake them, as falling back to sleep can be easier when melatonin is supplemented. If your sleep problems are primarily related to hormonal fluctuation rather than circadian disruption, other options on this list may be more suitable.

Combining Supplements with Sleep Habits

Supplements work best as part of a broader approach to sleep rather than as standalone fixes. Keeping a consistent bedtime and wake time, reducing screen light in the hour before bed, keeping the bedroom cool, and avoiding caffeine after early afternoon all support the same mechanisms that these supplements target. Tracking your sleep quality alongside which supplements you are using can help you identify which combination is most effective for your specific symptom pattern. Night sweats logged alongside sleep quality scores over several weeks often reveal patterns that are not obvious in the moment. PeriPlan allows you to log symptoms daily and view patterns over time, which is useful when you are experimenting with supplements and want to see whether they are making a measurable difference.

Related reading

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ArticlesBest Supplements for Perimenopause Anxiety
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Medical disclaimerThis content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. PeriPlan is not a substitute for professional medical advice. If you are experiencing severe or concerning symptoms, please contact your doctor or emergency services immediately.

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