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Best Supplements for Perimenopause Hair Thinning: What Actually Helps

Hair thinning during perimenopause is common and treatable. Here are the supplements most backed by evidence, plus what to expect and what to avoid.

6 min readFebruary 27, 2026

Why Hair Changes During Perimenopause

Hair thinning and increased shedding are among the most distressing symptoms many women notice during perimenopause. The primary driver is hormonal. As estrogen levels decline, its protective effect on hair follicles decreases, and androgens (male hormones present in all women) have a relatively stronger influence. This can cause follicles to shrink and produce thinner, shorter hairs over time. Thyroid imbalances, iron deficiency, and chronic stress, all of which become more common in this life phase, can compound the problem. Supplements can help address some of these underlying gaps, though they work best alongside a nutritious diet and a conversation with your doctor.

Biotin: What It Can and Cannot Do

Biotin is probably the most marketed supplement for hair, but the research is more nuanced than the packaging suggests. Biotin deficiency genuinely does cause hair loss, and supplementing can reverse that specific type of loss. However, most women eating a balanced diet are not biotin deficient. If you are already getting enough biotin from food, taking more will not make your hair grow faster or thicker. That said, biotin is water soluble and very safe at standard doses, so there is little harm in trying it. The doses used in hair supplements range from 1,000 to 5,000 mcg. One important note: high-dose biotin can interfere with thyroid lab tests, so let your doctor know if you are taking it before bloodwork.

Iron and Ferritin: Often Overlooked, Often the Real Problem

Low ferritin (stored iron) is one of the most commonly missed causes of hair loss in premenopausal and perimenopausal women. Ferritin levels can be in the normal range on standard lab tests while still being too low to support healthy hair growth. Many dermatologists who specialize in hair loss recommend a ferritin level of at least 70 ng/mL for optimal hair cycling. Ask your doctor specifically for a ferritin test if you are experiencing hair thinning and have not had one recently. Do not supplement with iron without testing first, as iron overload is also harmful. If your ferritin is genuinely low, iron supplementation can produce significant improvements in hair density over several months.

Collagen, Zinc, and Vitamin D: Supporting Roles

Several other nutrients play supporting roles in hair health and are worth considering. Collagen peptides provide amino acids that are building blocks for hair protein. Research on collagen for hair is still emerging, but many women report improvement in hair texture and thickness with consistent use. Zinc deficiency can cause hair shedding and is relatively common in women who do not eat much red meat or shellfish. A standard zinc supplement at 15 to 25 mg daily is reasonable if you suspect deficiency. Vitamin D deficiency is widespread and has been linked to alopecia. Getting your vitamin D levels checked and supplementing to bring them into the optimal range (around 50 to 70 ng/mL) is worthwhile for overall health and may help hair as well.

Saw Palmetto and DHT Blockers

Some supplements target the hormonal side of perimenopause hair thinning by reducing the effect of DHT, a potent androgen that shrinks hair follicles. Saw palmetto is the most studied natural DHT blocker and has shown promise in small studies for androgenic hair loss. It is available in capsule form and is generally well tolerated. Pumpkin seed oil is another option with some evidence behind it. These are not quick fixes. Most women who see results report needing 3 to 6 months of consistent use before noticing a difference. If you are on any hormone therapy or medications, check with your doctor before adding DHT-targeted supplements.

What to Avoid and Red Flags to Watch For

Be cautious of supplement blends that promise dramatic results without disclosing ingredient amounts. Proprietary blends often contain very small doses of each ingredient, too small to have a meaningful effect. Stick to supplements that list exact doses on the label. Avoid products with excessive fillers, artificial dyes, or unnecessary additives. Also be skeptical of before-and-after photos in marketing materials. Hair loss and regrowth photographs are easy to manipulate with lighting and styling, and they tell you nothing about what the supplement actually does. The most reliable evidence for any supplement comes from published clinical trials, which are worth searching for before spending money.

Tracking Your Progress Over Time

Hair changes are slow, which can make it hard to know whether a supplement is working. One helpful approach is to take consistent photos under the same lighting every four to six weeks. This gives you a visual record to compare over time rather than relying on day-to-day impressions. PeriPlan lets you log symptoms including hair changes so you can track patterns over months. Noting when you started a new supplement and how your hair feels over time gives you real data to share with your doctor rather than vague impressions. Combining this with lab testing to check iron and vitamin D levels gives you the clearest picture of what is actually driving the problem.

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Medical disclaimerThis content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. PeriPlan is not a substitute for professional medical advice. If you are experiencing severe or concerning symptoms, please contact your doctor or emergency services immediately.

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