Does ashwagandha help with weight gain during perimenopause?

Supplements

Ashwagandha is not a weight-loss supplement in the conventional sense, but it addresses one of the key drivers of perimenopausal weight gain: chronically elevated cortisol. As estrogen levels become erratic and begin to decline, your body grows more sensitive to stress hormones. High cortisol encourages fat storage, particularly around the abdomen, and drives cravings for calorie-dense foods. By helping to regulate the stress response, ashwagandha may support a metabolic environment that is less favorable to visceral fat accumulation.

The direct evidence linking ashwagandha to weight management is limited but worth knowing. A double-blind RCT published in the Journal of Evidence-Based Integrative Medicine (Choudhary et al., 2017) found that adults taking 300 mg of ashwagandha root extract twice daily for eight weeks had statistically significant reductions in body weight, BMI, and food cravings compared to placebo, along with lower perceived stress and serum cortisol. The effect sizes were modest, roughly 2 to 3 percent body weight reduction, and the study population was chronically stressed adults, not specifically perimenopausal women. There is no large-scale RCT in perimenopausal women showing meaningful fat loss from ashwagandha alone, so the evidence should be understood as supportive rather than definitive.

Perimenopause changes how and where your body stores fat in ways that feel sudden and frustrating. Declining estrogen shifts fat distribution from the hips and thighs toward the abdomen, and this metabolic change happens even without increases in calories. Visceral fat, the deep abdominal fat that wraps around organs, is metabolically active and produces inflammatory compounds that can further disrupt hormones and increase insulin resistance. Cortisol amplifies this process by activating glucocorticoid receptors in abdominal fat cells that specifically promote fat storage and resist breakdown when you try to lose weight. Insulin sensitivity also begins to decline during perimenopause, making it easier to gain weight and harder to lose it even with a consistent healthy diet and exercise routine. Ashwagandha does not directly influence estrogen, but by dampening HPA axis overactivation, it may interrupt the cortisol-visceral fat cycle at its root. Some early research also suggests ashwagandha may modestly support thyroid function by raising T3 and T4 levels, which matters because subclinical thyroid slowdown is common in perimenopausal women and can add several pounds even when nothing else about diet or activity has changed.

Studies focused on weight and stress have used 300 mg of standardized root extract (KSM-66 or equivalent) taken twice daily, for a total of 600 mg per day. Some practitioners use 500 mg once daily. Taking ashwagandha with food tends to reduce mild stomach discomfort. Standardized extracts with 5 percent withanolides are preferred over unstandardized powders for consistency. The weight-related benefits in trials emerged over 8 to 12 weeks of consistent use alongside existing diet and exercise habits, not as a replacement for them. Talk to your healthcare provider about the right dose for your situation.

For managing perimenopausal weight gain, ashwagandha pairs best with lifestyle strategies: resistance training, protein-forward meals, and consistent sleep, all of which also address cortisol and insulin sensitivity. Some women combine it with berberine, which targets insulin signaling more directly, though this combination has not been formally studied together. Avoid pairing ashwagandha with stimulant-based weight loss supplements, which can counteract its calming effect on the stress axis. If you take thyroid medication, discuss ashwagandha with your provider before starting, as it may alter thyroid hormone levels. Check with your provider if you take any prescription medications.

Do not expect dramatic or rapid results. The women likely to see the most benefit are those with high baseline stress and elevated cortisol driving their weight changes. If stress eating and comfort-food cravings are major factors for you, ashwagandha may have a noticeable impact on those urges within several weeks, as the Choudhary study specifically found reduced food cravings alongside weight changes. If your weight gain is primarily from insulin resistance, dietary patterns, or reduced physical activity, ashwagandha alone will not be sufficient and should be understood as one supportive piece within a broader strategy rather than a standalone solution.

Certain patterns of weight gain during perimenopause deserve medical evaluation rather than supplement experimentation. Rapid unexplained weight gain, significant swelling in the limbs and face, or fatigue paired with cold intolerance and constipation can all point to hypothyroidism, which is significantly underdiagnosed in perimenopausal women. A gain of more than five to ten pounds over a few months without any clear dietary explanation is worth investigating. Persistent weight gain despite consistent healthy habits is worth evaluating with a full metabolic panel, a thyroid panel (including TSH, free T3, and free T4), and fasting insulin level. These are relatively straightforward tests to request from your provider and can clarify what is actually driving the change rather than leaving you guessing.

Tracking your stress levels, food cravings, and sleep quality alongside weight gives you a clearer picture of whether ashwagandha is helping. If your perceived stress score and urge to eat emotionally both improve within four to six weeks, even if the scale moves slowly, that is a meaningful signal the supplement is doing something. Weight changes driven by cortisol and stress tend to respond more to subjective wellbeing improvements than they do to acute interventions. The PeriPlan app helps you log symptoms across your cycle so you can see connections between stress, sleep quality, and how your body feels day to day. Find it at https://apps.apple.com/app/periplan/id6740066498.

This content is for informational purposes only and does not replace medical advice. Always consult your healthcare provider about your specific situation.

Medical noteThis information is for educational purposes and is not a substitute for medical advice. If you are experiencing concerning symptoms, please consult your healthcare provider.

Related questions

Does ashwagandha help with sleep disruption during perimenopause?

Ashwagandha may help improve sleep quality during perimenopause, and the biological reasoning is solid. As estrogen and progesterone fluctuate and gra...

Does berberine help with perimenopause symptoms?

Berberine has solid evidence for metabolic benefits, and some of those benefits overlap meaningfully with what happens to your body during perimenopau...

Is ashwagandha safe during perimenopause?

Ashwagandha is generally considered safe for most women during perimenopause, though individual factors matter. As with any supplement, the quality of...

Can perimenopause cause weight gain?

Yes, weight gain can be connected to perimenopause. During this transition, fluctuating levels of estrogen and progesterone affect many body systems. ...

Track your perimenopause journey

PeriPlan's daily check-in helps you connect symptoms, mood, and energy to your cycle so you can spot patterns and take control.